Explore Dual-PhD carrier research, patent-pending modified-chitosan delivery, and 4 flexible cosmetic ODM tracks.
Claudin-1 membrane immunofluorescence (30 μm scale, ** p < 0.01) demonstrates superior tight-junction barrier restoration vs. conventional oat extract.
Claudin-1 membrane immunofluorescence (30 μm scale, ** p < 0.01) demonstrates superior tight-junction barrier restoration vs. conventional oat extract.
WUMO OatCalm+™ Supercritical Oat Alkaloid Complex (≥12% HPLC)
Water-soluble supercritical CO2 extracted (3.8× yield) and negative-charge-enriched Avena Sativa (Oat) Bran Extract standardized to ≥12% total oat alkaloids by HPLC (co-concentrating ≥7 natural avenanthramides A/B/C & caffeic acid derivatives), delivering >3× anti-inflammatory potency, TRPV1/PAR-2 neuro-calming, and Filaggrin/Claudin-1 barrier support.
≥12% HPLC total oat alkaloids (≥7 natural avenanthramides A, B, C + caffeic acid derivatives)3.8× extraction yield via supercritical CO2 + negative-charge-guided enrichment>3× in-vitro anti-inflammatory inhibition vs. conventional oat extract; blocks TRPV1 & PAR-2Upregulates Filaggrin (FLG) & Claudin-1 tight junctions; ≥95% retention after 3 months at 45 °C
Review specifications, files, and next-step support before requesting samples.
- Confirm the peptide name, CAS, and core specifications
- Check typical applications and document availability
- Use one inquiry path for pricing, files, samples, or project discussion
Direct Answer
Ingredient identity for buyer review
Confirm naming, CAS, document scope, and inquiry intent before sample, MOQ, lead-time, or bulk quotation discussion.
- Market Name
- WUMO OatCalm+™ (Supercritical CO2 Enriched Oat Bran Alkaloid Complex)
- INCI Name
- Avena Sativa (Oat) Bran Extract (aqueous cosmetic delivery system; full solvent breakdown on TDS)
- Common Review Documents
- TDS, HPLC Assay COA, % INCI Breakdown, 16-Section English GHS SDS
- Buyer Intent
- Post-peel/laser comfort masks, sensitive-skin serums, dual-phase capsule creams, and children/eye-safe ISO 22716 emulsions
Specifications
Specifications
Review the core data firstCheck the technical points buyers usually confirm before pricing or sample discussion.
Market NameWUMO OatCalm+™ (Supercritical CO2 Enriched Oat Bran Alkaloid Complex)
INCI NameAvena Sativa (Oat) Bran Extract (aqueous cosmetic delivery system; full solvent breakdown on TDS)
Quantitative Assay (HPLC)Total Oat Alkaloid Complex ≥ 12.0% (co-enriched ≥7 natural oat alkaloids incl. Avenanthramides A, B, C)
Extraction ProcessSelective Supercritical CO2 Extraction (3.8× yield vs. water/ethanol) + Surface Negative-Charge Enrichment
AppearanceWater-soluble clear transparent to pale-yellow liquid
Recommended Dosage & pH0.5% – 3.0% w/w · Applicable formula pH 4.5 – 7.0
Accelerated Thermal Stability≥ 95% active alkaloid retention after 3 months at 45 °C
Formulation & Packaging NoteRecommend light-protective or airless packaging; avoid direct co-formulation with strong cationic preservatives (e.g., polyaminopropyl biguanide / PHMB)
Common Review DocumentsTDS, HPLC Assay COA, % INCI Breakdown, 16-Section English GHS SDS
Buyer IntentPost-peel/laser comfort masks, sensitive-skin serums, dual-phase capsule creams, and children/eye-safe ISO 22716 emulsions
+219% 8-hour ex-vivo skin permeation, -32.0% ACh inhibition at 1/10th dose, and GQI 33-subject trial data.
Inspect on-site booth photos, ISO 22716:2007 cosmetic GMP certificate, and buyer Q&A from Guangzhou.
Typical Applications
Typical Applications
- Post-AHA/PHA peel, retinoid, and aesthetic-clinic cosmetic comfort serums & hydrogel masks
- Sensitive-skin barrier creams, dual-phase capsule creams, and airless body lotions
- Periorbital and gentle family skincare lines (within Suzhou Xilin ISO 22716 eye-care & children’s cosmetic scope)
- Soothing scalp comfort tonics paired with Menthol Citrate Ester and Palmitoyl Tripeptide-8
MOQ / Lead Time / Samples
Commercial follow-up usually starts here.
- Sample availability can be confirmed for qualified projects
- MOQ and lead time are shared during inquiry
- Pricing and file requests can be handled together
Why buyers trust WUMO
Real content, documented — not guesswork
In peptide sourcing, chromatographic purity and delivered quantity require separate evaluation. We keep purity and labeling basis distinct on available documentation, so buyers can review analytical parameters for their quoted batch before ordering.
Purity vs quantity distinction
Purity (%) and reported quantity are distinct analytical parameters. Review purity and reported quantity separately, and confirm the labeling and assay basis for the batch proposed for your order.
Batch-specific documents
Batch documentation reflects the specific lot produced. Ask which batch-specific documents are available for the quoted lot, including COA and supporting HPLC or MS records where applicable.
Documented before commitment
Ingredient identity (INCI / CAS), specification sheet, and SDS are available for technical review. Confirm documentation for the batch proposed for your order before purchase.
Documents Available
Documents Available
Spec
WUMO OatCalm+™ Technical Data Sheet (TDS) & HPLC ≥12% Alkaloid Spec
Purity profile reference for the quoted project or batch where available.
Request this file through the inquiry path below.
COA
Batch Certificate of Analysis (COA) & 16-Section English GHS SDS
Batch-level quality summary for buyer-side file review.
Request this file through the inquiry path below.
Analytical File
TRPV1 / Cytokine / Claudin-1 Preclinical Soothing Summary
Request scope and availability through the B2B inquiry path.
Request this analytical file through the inquiry path below.
Overview
Overview
Conventional water- or ethanol-extracted oat waters carry only trace parts-per-million of avenanthramides and often brown or lose potency during storage. WUMO OatCalm+™ pairs selective supercritical CO2 extraction (3.8× higher yield) with surface negative-charge enrichment to standardize at least 7 natural oat bran alkaloids—including Avenanthramides A, B, and C plus caffeic acid derivatives—to ≥12% total alkaloids by HPLC.
Across 3 months of accelerated storage at 45 °C, WUMO OatCalm+™ retains ≥95% active alkaloid content while remaining water-soluble and clear for serums, mists, hydrogel masks, and barrier emulsions. Read the full WUMO OatCalm+™ technical dossier →
Details
Details
Neuro-Sensory Calming & Epidermal Barrier Pathways
- Neuro-Sensory Receptor Blockade (
TRPV1/PAR-2/ Mast Cells): Inhibits heat-sting receptorTRPV1, protease-activated receptorPAR-2, and Substance P-induced mast-cell degranulation to calm stinging, burning, itching, and redness after exfoliants or cosmetic procedures. - Over 3× Cytokine Suppression vs. Conventional Oat Extract: At equal concentrations in LPS-challenged cell models, restores cell viability, speeds 24-hour scratch closure and EdU proliferation, clears intracellular ROS, and delivers more than 3-fold stronger inhibition of TNF-α, IL-1β, and IL-6.
- Filaggrin & Claudin-1 Tight-Junction Support: qPCR and membrane immunofluorescence confirm upregulation of Filaggrin (
FLG) and continuous Claudin-1 tight junctions. In murine DNFB sensitization studies, reduces serum IgE (ng/mL), erythema, scaling, and inflammatory epidermal thickening.
Formulation & Packaging Guidelines
- Dosage & pH Window: Add at 0.5%–3.0% w/w within formula pH 4.5–7.0.
- Preservative & Container Compatibility: Because enrichment relies on negatively charged phenolic alkaloids, avoid direct co-formulation with strong cationic preservatives such as Polyaminopropyl Biguanide (PHMB) to prevent ionic haze. Use UV-shielded or airless packaging to maintain pale clarity.
Related Peptides
Compare related ingredients without restarting the review.
Peptide Raw Materials
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Electrostatic 6:1 hydroxyethyl-chitosan self-assembled transdermal salmon DNA (Sodium DNA / PDRN) delivery system compressing 539.5 nm free PDRN (PDI 0.53) into monodisperse 188.0 ± 4.32 nm nanospheres (PDI 0.14). Verified +494.44% 4-hour ex vivo porcine skin Raman permeation and +260% 8-hour in vivo dermal fluorescence.
+494.44% 4h ex vivo porcine skin Raman permeation (~6× faster barrier entry)539.5 nm (PDI 0.53) → 188.0 ± 4.32 nm (PDI 0.14) monodisperse 6:1 co-assembly+260% 8h in vivo dermal fluorescence (p < 0.001) & macropinocytosis uptake
Peptide Raw Materials
AHPX+ (Acetyl Hexapeptide-8 Pro) Chitosan Carrier Complex
Carrier-enhanced 1,000 ppm (0.1%) Acetyl Hexapeptide-8 aqueous cosmetic delivery complex paired with Suzhou Xilin’s patent-pending modified chitosan carrier (CN120248173A). Demonstrated +82% (2h) and +219% (8h) ex-vivo skin permeation vs. unmodified hexapeptide and 28-day human split-face substantiation (GQI, n = 33).
Patent-pending modified chitosan carrier (CN120248173A)+219% 8h ex-vivo skin uptake (3.19× vs. free peptide)28-day GQI split-face human study (n = 33)
Peptide Raw Materials
Palmitoyl Tripeptide-8
Cosmetic peptide commonly reviewed for soothing-oriented and skin-comfort formulation projects in serums, creams, masks, and related facial care formats.
COA/SDS AvailableSample SupportBulk Inquiry
Finished Formulation Concepts
One-Step Clear-Turning Salmon DNA (PDRN+) & Peptide Hydrogel Mask ODM
One-step milky-to-clear cast hydrogel mask ODM pairing AHPX+ (30 ppm), WUMO PDRN+™ (200 ppm), <0.5 EU/mL Type III Collagen & OatCalm+™.
Finished Formulation Concepts
Dual-Phase Peptide & Nano-PDRN Suspended Capsule Cream OEM/ODM
Suspended shear-burst peptide & nano-PDRN capsules in a soothing OatCalm+™ & <0.5 EU/mL Type III Collagen gel-cream for ISO 22716 OEM/ODM.
Cosmetic Pro-Peptide Delivery & Flexible ISO 22716 ODM
Developing a mid-to-high-end skincare or scalp SKU with WUMO OatCalm+™ Supercritical Oat Alkaloid Complex (≥12% HPLC)?
Compare neat raw actives, AHPX+ modified-chitosan delivery complex
(CN120248173A, +219% 8h skin permeation), bulk compounded
kg / liter semi-finished bases, and phased custom-packaged ODM at
Suzhou Xilin Technology Co., Ltd. (ISO 22716:2007 Cert. 27825-2025GPOC00009R000,
covering liquid & eye-care/cream scope): explore our Pro-Peptide Science & ODM Hub or Finished Skincare OEM / ODM Service.
Request WUMO OatCalm+™ Supercritical Oat Alkaloid Complex (≥12% HPLC) Batch COA, Sample, or Bulk / ODM Pricing
Share your target format (raw active by g/kg, bulk semi-finished base by kg/liter, or custom-packaged ODM), target active %, and destination market (EU PIF/CPSR, UK SCPN, US MoCRA, ANVISA).