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Synthesized by esterifying L-menthol with citric acid for clean dispersion in water-based scalp tonics and shampoos.
Synthesized by esterifying L-menthol with citric acid for clean dispersion in water-based scalp tonics and shampoos.
Menthol Citrate Ester Scalp-Care Active
Amphiphilic cooling scalp-care ester synthesized from L-menthol and citric acid for low-ethanol aqueous scalp serums, clarifying gels, sprays, and Peptide + Aminexil hair-care formulations. Demonstrated 90.59%–95.29% in-vitro Malassezia furfur contact inhibition at 1.5%–2.0% in tested shampoo base.
Esterified L-menthol + citric acid amphiphilic structureDisperses in water-based scalp serums without heavy alcohol90.59%–95.29% in-vitro M. furfur inhibition (1.5%–2.0% shampoo test)Pairs with Aminexil, Acetyl Tetrapeptide-3 & GHK-Cu
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Direct Answer
Ingredient identity for buyer review
Confirm naming, CAS, document scope, and inquiry intent before sample, MOQ, lead-time, or bulk quotation discussion.
- Market Name
- Menthol Citrate Ester (Amphiphilic Scalp-Care Ester)
- INCI Name
- Menthyl Citrate / Menthol Citrate Ester (confirm exact regional INCI on TDS)
- Synonym
- Citric Acid L-Menthol Ester
- Typical Formats
- Scalp serums, follicle tonics, clarifying scalp gels, clarifying & scalp-refreshing cosmetic shampoos
- Common Review Documents
- TDS, Batch COA, 16-Section GHS SDS, Supplier In-Vitro Test Summary
- Buyer Intent
- Alcohol-reduced scalp microbiome & peptide hair-care formulation projects
Quick Answer
Menthol Citrate Ester: low-ethanol scalp dispersion & Aminexil co-formulation answer
B2B sourcing noteSynthesized by esterifying L-menthol with citric acid, Menthol Citrate Ester provides an amphiphilic cooling scalp-care active that disperses cleanly in water-based and low-ethanol shampoos, scalp gels, and leave-on follicle tonics—showing 90.59% (at 1.5%) to 95.29% (at 2.0%) in-vitro Malassezia furfur inhibition after 3 minutes of contact in supplier shampoo testing.
Naming comparison table
| Name / term | How buyers should read it | RFQ action |
|---|---|---|
| Menthol Citrate Ester | Amphiphilic organic acid-terpene ester for cosmetic scalp-care formulations. | Eliminates high-ethanol sting associated with crystalline free L-menthol. |
| Aminexil (Diaminopyrimidine Oxide) Pairing | Complementary follicle-anchoring cosmetic active in leave-on scalp tonics. | Combine at 1.0%–2.0% Menthol Citrate Ester for balanced cooling & microbiome hygiene. |
| GHK-Cu Scalp Pairing | Neutral-pH leave-on peptide scalp essence compatibility. | Verify final pH 5.5–6.5 when pairing with Copper Tripeptide-1. |
B2B specification review table
| Review item | Buyer check |
|---|---|
| Recommended use level | 0.5%–2.0% w/w across shampoos, scalp cleansing gels, and leave-on scalp sprays/tonics. |
| In-vitro contact reference | 90.59% (1.5%) to 95.29% (2.0%) Malassezia furfur inhibition at 3-minute contact in tested shampoo base (cosmetic R&D context only, not an OTC drug claim). |
| Supply routes | 1 kg–25 kg active packs, bulk kg/liter scalp bases, or turnkey ODM at Suzhou Xilin (ISO 22716:2007). |
Use this internal resource to keep sourcing, documentation, and RFQ discussion on the same page.
Use this internal resource to keep sourcing, documentation, and RFQ discussion on the same page.
Specifications
Specifications
Review the core data firstCheck the technical points buyers usually confirm before pricing or sample discussion.
Market NameMenthol Citrate Ester (Amphiphilic Scalp-Care Ester)
INCI NameMenthyl Citrate / Menthol Citrate Ester (confirm exact regional INCI on TDS)
SynonymCitric Acid L-Menthol Ester
AppearanceClear to pale-yellow viscous liquid / dispersible ester
Recommended Dosage0.3% – 2.0% w/w (0.3%–0.8% leave-on scalp tonics; 1.0%–2.0% rinse-off scalp cleansers)
Typical FormatsScalp serums, follicle tonics, clarifying scalp gels, clarifying & scalp-refreshing cosmetic shampoos
Common Review DocumentsTDS, Batch COA, 16-Section GHS SDS, Supplier In-Vitro Test Summary
Buyer IntentAlcohol-reduced scalp microbiome & peptide hair-care formulation projects
Explore Dual-PhD carrier research, patent-pending modified-chitosan delivery, and 4 flexible cosmetic ODM tracks.
+219% 8-hour ex-vivo skin permeation, -32.0% ACh inhibition at 1/10th dose, and GQI 33-subject trial data.
Inspect on-site booth photos, ISO 22716:2007 cosmetic GMP certificate, and buyer Q&A from Guangzhou.
Typical Applications
Typical Applications
- Leave-on peptide scalp serums with Acetyl Tetrapeptide-3, Biotinoyl Tripeptide-1, or Copper Tripeptide-1
- Diaminopyrimidine Oxide (Aminexil) follicle-conditioning tonics requiring sustained mild cooling
- Clarifying scalp pre-wash gels and sulfate-free shampoos
- Refreshing scalp-comfort mists and post-workout hair sprays
MOQ / Lead Time / Samples
Commercial follow-up usually starts here.
- Sample availability can be confirmed for qualified projects
- MOQ and lead time are shared during inquiry
- Pricing and file requests can be handled together
Why buyers trust WUMO
Real content, documented — not guesswork
In peptide sourcing, chromatographic purity and delivered quantity require separate evaluation. We keep purity and labeling basis distinct on available documentation, so buyers can review analytical parameters for their quoted batch before ordering.
Purity vs quantity distinction
Purity (%) and reported quantity are distinct analytical parameters. Review purity and reported quantity separately, and confirm the labeling and assay basis for the batch proposed for your order.
Batch-specific documents
Batch documentation reflects the specific lot produced. Ask which batch-specific documents are available for the quoted lot, including COA and supporting HPLC or MS records where applicable.
Documented before commitment
Ingredient identity (INCI / CAS), specification sheet, and SDS are available for technical review. Confirm documentation for the batch proposed for your order before purchase.
Technical & Analytical Video Briefs
Menthol Citrate Ester Scalp-Care Active — Video Walkthroughs & Study Benchmarks
Watch analytical verification, solubility & specification parameters, transdermal delivery data, and reference formulation study walkthroughs with full transcripts.
Scalp Care Active Brief1:05
Scalp-Care Formulation Brief · 1:05
Menthol Citrate Ester: Amphiphilic Scalp-Care Active Dispersion & In-Vitro Study Overview
Formulation overview of Menthol Citrate Ester — a cooling scalp-care active synthesized by esterifying L-menthol with citric acid. Explains its amphiphilic dispersion in aqueous and multi-phase scalp formulas (shampoos, scalp cleansing gels, scalp sprays) and supplier in-vitro contact testing against Malassezia furfur at 1.5%–2.0%.
Verification scope:Scalp-care co-formulation active, aqueous dispersion & supplier in-vitro test summary
Jump to timestamp:
Key Verifiable Points & Parameters
- Chemistry & Structure: Synthesized via esterification of L-menthol with citric acid, combining a cooling menthol sensory profile with an amphiphilic structure.
- Formulation Compatibility: Disperses more readily than free menthol in water-based and multi-phase scalp systems, including shampoos, scalp cleansing gels, and leave-on scalp sprays.
- Supplier In-Vitro Contact Data (3-Minute Contact): A tested shampoo containing 1.5% to 2.0% Menthol Citrate Ester showed 90.59% (at 1.5%) to 95.29% (at 2.0%) inhibition of Malassezia furfur in laboratory testing.
- Scalp-Care Co-Formulation Context: Evaluated alongside scalp-care actives such as Diaminopyrimidine Oxide (Aminexil) and Copper Tripeptide-1 (GHK-Cu) in OEM/ODM hair and scalp programs.
Read Verbatim Transcript, Summary & Verification Scope
Summary:Formulation overview of Menthol Citrate Ester — a cooling scalp-care active synthesized by esterifying L-menthol with citric acid. Explains its amphiphilic dispersion in aqueous and multi-phase scalp formulas (shampoos, scalp cleansing gels, scalp sprays) and supplier in-vitro contact testing against Malassezia furfur at 1.5%–2.0%.
Verbatim Audio / Visual Transcript:A refreshing scalp care formula starts with the right ingredient. Menthol citrate ester is made by esterifying L-menthol with citric acid. It retains a fresh menthol sensation. Its amphiphilic structure helps it disperse in water-based and multi-phase formulations. Formulators can explore it in shampoos, scalp cleansing gels, and scalp sprays. In supplier laboratory testing, a shampoo with 1.5% to 2.0% menthol citrate ester showed 90.59% to 95.29% inhibition of Malassezia furfur after 3 minutes of contact (supplier-reported in-vitro data for the tested formula). Bring a clean cooling sensation to your next scalp care concept with menthol citrate ester. For cosmetic formulation development.
Editorial & Verification Scope Note:Menthol Citrate Ester is a non-peptide cosmetic scalp-care functional ester supported in WUMO / Suzhou Xilin scalp formulation programs. In-vitro Malassezia furfur inhibition figures apply only to the supplier-tested shampoo formula under 3-minute laboratory contact conditions and do not constitute an anti-dandruff drug or medical claim.
Documents Available
Documents Available
Spec
Menthol Citrate Ester Technical Data Sheet (TDS)
Request scope and availability through the B2B inquiry path.
Request this file through the inquiry path below.
COA
Batch Certificate of Analysis (COA)
Batch-level quality summary for buyer-side file review.
Request this file through the inquiry path below.
Safety
16-Section English GHS Safety Data Sheet (SDS)
Safety document requested for internal purchasing and handling review.
Request this safety document through the inquiry path below.
Overview
Overview
Menthol Citrate Ester is a functional scalp-care co-active engineered by esterifying L-menthol with tricarboxylic citric acid. Free crystalline L-menthol requires high ethanol or heavy solubilizer loads in aqueous hair tonics—often stinging sensitive scalps and destabilizing delicate cosmetic peptides. By introducing hydrophilic citrate carboxyl groups alongside the terpene ring, Menthol Citrate Ester achieves smooth amphiphilic dispersion across aqueous and surfactant scalp vehicles while delivering a sustained, low-sting cooling profile.
Details
Details
Formulation Advantages in Peptide & Aminexil Scalp Systems
- Low-Ethanol Aqueous Dispersion: Enables clear or micro-dispersed leave-on scalp serums paired with water-soluble peptides (Acetyl Tetrapeptide-3, Copper Tripeptide-1) without 30%–50% denatured alcohol.
- Supplier In-Vitro Scalp Hygiene Benchmark: In supplier laboratory testing under a 3-minute contact protocol, a shampoo base formulated with
1.5%and2.0%Menthol Citrate Ester demonstrated 90.59% (at 1.5%) and 95.29% (at 2.0%) inhibition of Malassezia furfur relative to control. - pH & Peptide Note: Check final pH after dispersion (target
pH 5.0 – 6.5for leave-on peptide tonics; if pairing with Copper Tripeptide-1, buffer topH 5.8 – 6.8and verify color stability in accelerated 45 °C testing as citrate moieties can interact with divalent copper at high ratios).
Related Peptides
Compare related ingredients without restarting the review.
Hair & Scalp Care Actives
Aminexil (Diaminopyrimidine Oxide)
Hair-care active commonly reviewed for scalp-care and hair-care formulation projects in serums, tonics, shampoos, and related product formats.
COA/SDS AvailableSample SupportBulk Inquiry
Hair & Scalp Care Actives
Acetyl Tetrapeptide-3
Cosmetic peptide commonly reviewed for scalp-care and hair-care formulation projects in serums, tonics, shampoos, and related hair-care formats.
COA/SDS AvailableSample SupportBulk Inquiry
Peptide Raw Materials
Copper Tripeptide-1 (GHK-Cu)
Cosmetic peptide commonly reviewed for premium skin-care, skin-comfort, and multi-functional facial care formulation projects in serums, creams, masks, and related product formats.
COA/SDS AvailableSample SupportBulk Inquiry
FAQ
Frequently Asked Questions
Does the Malassezia furfur test result make Menthol Citrate Ester an anti-dandruff drug active?
No. Menthol Citrate Ester is supplied strictly as a cosmetic scalp-conditioning and sensory-cooling ingredient; the 3-minute laboratory contact test reflects supplier in-vitro shampoo evaluation only.
Does the in-vitro Malassezia furfur data authorize medical anti-dandruff drug claims?
No. Menthol Citrate Ester is supplied strictly as a cosmetic sensory cooling and scalp-conditioning ester. Supplier in-vitro figures reflect a 3-minute laboratory shampoo contact test and do not constitute OTC anti-dandruff drug approval (such as US FDA OTC monograph claims).
Can Menthol Citrate Ester be combined with Aminexil in finished OEM scalp tonics?
Yes. Suzhou Xilin Technology Co., Ltd. (ISO 22716:2007 cosmetics scope) formulates turn-key and bulk semi-finished scalp tonics combining Diaminopyrimidine Oxide (Aminexil), Menthol Citrate Ester, and hair-care peptides.
Cosmetic Pro-Peptide Delivery & Flexible ISO 22716 ODM
Developing a mid-to-high-end skincare or scalp SKU with Menthol Citrate Ester Scalp-Care Active?
Compare neat raw actives, AHPX+ modified-chitosan delivery complex
(CN120248173A, +219% 8h skin permeation), bulk compounded
kg / liter semi-finished bases, and phased custom-packaged ODM at
Suzhou Xilin Technology Co., Ltd. (ISO 22716:2007 Cert. 27825-2025GPOC00009R000,
covering liquid & eye-care/cream scope): explore our Pro-Peptide Science & ODM Hub or Finished Skincare OEM / ODM Service.
Request Menthol Citrate Ester Scalp-Care Active Batch COA, Sample, or Bulk / ODM Pricing
Share your target format (raw active by g/kg, bulk semi-finished base by kg/liter, or custom-packaged ODM), target active %, and destination market (EU PIF/CPSR, UK SCPN, US MoCRA, ANVISA).